The Medford to Seattle route connects Rogue Valley International Medford Airport (MFR) in US with Seattle–Tacoma International Airport (SEA) in US. This short-haul flight covers approximately 352 miles (566 km) with a typical flight time of 55m. This route is served by 3 airlines: SkyWest, Horizon, PenAir. AirportRoutes has tracked 21 unique flight numbers on this route.
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The Medford (MFR) → Seattle (SEA) route links Southern Oregon with the Pacific Northwest’s largest metro area over 352 miles (566 km). Nonstop flights typically take about 1 hour 10 minutes to 1 hour 30 minutes, making it a time-saving alternative to the long drive and mountain passes. Travelers choose this hop for quick access to Seattle’s corporate hubs, major events, and international connections at SEA, while Medford serves as a convenient gateway to the Rogue Valley, Crater Lake region, and Oregon wine country. The route is popular with business travelers, weekend city-breakers, and flyers connecting onward to Alaska, Asia, and Europe. Expect smooth, short-haul service with limited in-flight amenities, but efficient point-to-point convenience.
Book early for the best USD fares, especially around summer weekends and holiday periods when Seattle demand spikes. If your schedule is flexible, midweek departures often price lower and face shorter lines. At MFR, arrive about 75–90 minutes before departure; the airport is compact, but morning banks can create brief security queues. At SEA, plan extra time for longer walks, crowded checkpoints, and potential gate changes—using the airport app and checking the terminal map helps. Choose a carry-on-friendly setup for this 352-mile (566 km) flight; overhead space can be tight on regional aircraft. Weather can affect operations in winter, so consider earlier flights to reduce cascade delays and keep a buffer for connections.
Seattle pairs iconic waterfront scenery with neighborhoods that feel distinct block by block. Start at Pike Place Market for local crafts, fresh seafood, and coffee culture, then head to the Space Needle and Chihuly Garden and Glass for skyline views and art. The Seattle Waterfront and ferries offer easy day trips to Bainbridge Island, while Discovery Park and Kerry Park deliver classic vistas of Puget Sound and Mount Rainier on clear days. Food is a highlight: try Dungeness crab, salmon, oyster bars, and Seattle’s espresso scene, plus inventive Asian cuisines in the International District. Popular areas to explore include Capitol Hill for nightlife, Belltown for dining, and Ballard for breweries and maritime history.
For the most reliable weather, fly June through September, when Seattle is typically drier and daylight is long—though prices in USD often peak in mid-summer. April–May and October can offer a good balance of milder crowds and moderate fares, with variable showers. November–March is the wettest period and can bring occasional winter disruptions; it’s often cheaper outside holiday weeks. Major demand spikes align with summer travel, Seafair (late July–early August), and year-end holidays.
Rogue Valley International Medford Airport
KMFRMFRSeattle–Tacoma International Airport
KSEASEA3
Operators21
Tracked Flights352
Miles55m
Flight Duration
| Day | Flights Observed | Frequency | Activity |
|---|---|---|---|
| Monday | 47 | 12% |
|
| Tuesday | 58 | 15% |
|
| Wednesday | 55 | 15% |
|
| Thursday | 50 | 13% |
|
| Friday | 63 | 17% |
|
| Saturday | 56 | 15% |
|
| Sunday | 47 | 12% |
|
Pattern Analysis
| Airline | Flight Numbers | Aircraft Type | Typical Time | Days Active | Last Seen | Status |
|---|---|---|---|---|---|---|
|
Horizon
QXE
/ QX
|
|
E75L | 17:36 5:36 PM (Representative) |
M
T
W
T
F
S
S
|
May 9, 2026 | Active |
|
PenAir
NLA
|
E75L | 17:44 5:44 PM (Representative) |
M
T
W
T
F
S
S
|
Mar 6, 2026 | Active | |
|
SkyWest
SKW
/ OO
|
|
E75L | 17:25 5:25 PM (Representative) |
M
T
W
T
F
S
S
|
May 9, 2026 | Active |
Time Information
Times are shown in the departure airport's local timezone (KMFR - America/Los_Angeles).