| IATA | ICAO | Name | City | Type |
|---|---|---|---|---|
| OYC | GF-0004 | Camopi Airport | Camopi | Small Airport |
| - | GF-0009 | Camp Maripas Seaplane Base | Kourou | Seaplane Base |
| CAY | SOCA | Cayenne – Félix Eboué Airport | Matoury | Large International Airport Scheduled |
| - | GF-0006 | Guiana Space Centre East Heliport | Kourou | Heliport |
| - | GF-0005 | Guiana Space Centre West Heliport | Kourou | Heliport |
| - | GF-0007 | Île Royale Heliport | Kourou | Heliport |
| - | GF-0001 | Kourou Airport | Kourou | Small Airport |
| - | GF-0013 | Montsinery Seaplane Base | Montsinery | Seaplane Base |
| - | GF-0002 | Ouanary Airport | Ouanary | Small Airport |
| REI | SOOR | Régina Airport | Régina | Small Airport |
| - | GF-0008 | Rosemond Hospital Helipad | Cayenne | Heliport |
| - | GF-0003 | Saint-Élie Airport | Saint-Élie | Small Airport |
| OYP | SOOG | Saint-Georges-de-l'Oyapock Airport | Saint-Georges-de-l'Oyapock | Medium Airport |
| - | SOOY | Sinnamary Airport | Sinnamary | Small Airport |